Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Occupational asthma caused by palladium.

M Daenen1, P Rogiers, C Van de Walle

  • 1Pneumology, K.U. Leuven, Belgium.

The European Respiratory Journal
|June 3, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association Between Occupational Exposure and Sinus Surgery Outcomes in Chronic Rhinosinusitis: A Prospective Study.

Allergy·2025
Same author

Rapidly progressive silicosis previously diagnosed as pulmonary TB in mineworkers.

IJTLD open·2025
Same author

Hypoxaemia and risk of asphyxia during underground work in artisanal cobalt mines.

Occupational medicine (Oxford, England)·2024
Same author

Impact of acute exacerbations of COPD on patients' health status beyond pulmonary function: A scoping review.

Pulmonology·2022
Same author

Short-term health effects in the general population following a major train accident with acrylonitrile in Belgium.

Environmental research·2016
Same author

A chest physician's guide to mechanisms of sinonasal disease.

Thorax·2015

Occupational asthma can be caused by palladium sensitization. This case report details a worker who developed asthma and rhinoconjunctivitis due to palladium exposure in an electroplating bath.

Area of Science:

  • Occupational Medicine
  • Immunology
  • Toxicology

Background:

  • Occupational asthma is commonly linked to platinum salts.
  • Sensitization to other precious metals like palladium and rhodium is known in platinum refinery workers.
  • However, isolated occupational asthma from palladium sensitization has not been previously reported.

Observation:

  • A previously healthy worker in an electroplating facility developed occupational rhinoconjunctivitis and asthma.
  • The worker was exposed to palladium fumes with no platinum exposure.
  • Diagnostic tests confirmed palladium sensitization.

Findings:

  • Skin-prick tests were positive for palladium, specifically with Pd(NH3)4Cl2, but negative for platinum salts.
  • Bronchial provocation tests with palladium chloride induced a significant decrease in lung function (FEV1 -35%).

Related Experiment Videos

  • A control subject exposed to palladium showed no adverse reaction.

    • Implications:

    • This case establishes that isolated palladium sensitization can cause occupational asthma.
    • Respiratory exposure to palladium is identified as a novel cause of metal-induced occupational asthma.
    • Highlights the need for awareness and diagnostic consideration of palladium in occupational respiratory diseases.