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Does a relationship exist between ioduria, magnesiuria and calciuria?

A Simecková1, V Zamrazil, J Cerovská

  • 1Institute of Endocrinology, Prague, Czech Republic.

Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
|June 3, 2000
PubMed
Summary

This study found that higher ioduria (iodine levels in urine) correlates with increased calciuria, magnesiuria, and creatininuria in Czech adults and children. These findings suggest a link between iodine status and mineral excretion across a wide age range.

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Area of Science:

  • Biochemistry
  • Clinical Chemistry
  • Human Physiology

Background:

  • Urinary iodine concentration (ioduria) is a key indicator of iodine intake.
  • Urinary calcium (calciuria), magnesium (magnesiuria), and creatinine (creatininuria) levels reflect various physiological processes and potential imbalances.
  • Understanding the interrelationships between these urinary markers is crucial for assessing population health and nutritional status.

Purpose of the Study:

  • To investigate the relationship between ioduria and calciuria, magnesiuria, and creatininuria.
  • To determine if these relationships differ between children and adults.
  • To assess the influence of sex on these associations.

Main Methods:

  • A randomly selected population sample from the Czech Republic was studied.

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  • Individual urinary parameters (ioduria, calciuria, magnesiuria, creatininuria) were measured in overnight fasting urine samples.
  • Concentrations were determined using standardized methods (WHO/ICCIDD).
  • Main Results:

    • A parallel increase in calciuria, magnesiuria, and creatininuria was observed with increasing ioduria.
    • Positive correlations were found between ioduria and calciuria, magnesiuria, and creatininuria.
    • These correlations were consistent in both children and adults aged 6-93 years, irrespective of sex.

    Conclusions:

    • Urinary iodine levels are positively associated with urinary calcium, magnesium, and creatinine excretion in the general population.
    • This relationship appears consistent across a broad age spectrum and is not influenced by sex.
    • Further research may explore the underlying mechanisms and clinical implications of these observed correlations.