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A new stilbene diglycoside from Rheum undulatum
1Korea Ginseng Institute, Chung-Ang University, Ansung. sungkwon@cau.ac.kr
Archives of Pharmacal Research
|June 3, 2000
Summary
Researchers identified a new stilbene diglycoside, piceatannol-3, 4'-O-beta-D-diglucopyranoside, and three other compounds from Korean rhubarb rhizomes (Rheum undulatum). These compounds were confirmed using chemical and spectral analysis.
Area of Science:
- Phytochemistry
- Natural Products Chemistry
- Pharmacognosy
Background:
- Korean rhubarb (Rheum undulatum) rhizomes are a source of bioactive compounds.
- Previous research has explored the chemical constituents of various Rheum species.
Purpose of the Study:
- To isolate and characterize novel and known compounds from cultivated Korean rhubarb rhizomes.
- To identify the chemical structures of isolated compounds using spectroscopic and chemical methods.
Main Methods:
- Extraction of compounds from Rheum undulatum rhizomes.
- Isolation and purification of chemical constituents.
- Structure elucidation using Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS).
- Chemical derivatization and comparison with known standards.
Main Results:
- A new stilbene diglycoside, piceatannol-3, 4'-O-beta-D-diglucopyranoside, was isolated and identified.
- Three known compounds: desoxyrhaponticin, emodin-1-O-beta-D-glucopyranoside, and physcion-8-O-b-D-glucopyranoside, were also identified.
- The structures of all four compounds were confirmed through comprehensive spectral and chemical analyses.
Conclusions:
- The study successfully identified a novel stilbene diglycoside from Korean rhubarb.
- This research contributes to the phytochemical understanding of Rheum undulatum and its potential natural products.