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Genetic polymorphism of 4 STR loci on chromosome 17 in Chinese Han
1Department of Medical Genetics, Shandong Medical University, Jinan, Shandong, 250012 P. R. China. Genet@public.jn.sd.cn
Objective:
To analyze genetic polymorphism of D17S1290, D17S1293, D17S1303 and D17S1308 in Chinese Hans.
Methods:
Fifty unrelated individuals were analyzed by PCR amplification fragment length polymorphism analysis method.
Results:
9, 7, 5, 5 alleles were observed at these 4 STR loci respectively, the genotypes distributions in Chinese Hans were in accordance with Hardy-Weinberg equilibrium, the expected heterozygosities for these loci were 0.770, 0.828, 0.608, 0.669 respectively, the polymorphism information contents(PIC) were 0.763, 0.820, 0.602, 0.662 respectively.
Conclusion:
The results demonstrate these 4 STR loci can be used for genetic analysis.