Normal rate of cerebrospinal fluid formation five years after bilateral choroid plexectomy. Case report

Area of Science:

• Neuroscience
• Pediatric Neurology
• Cerebrospinal Fluid Dynamics

Background:

• Communicating hydrocephalus is a condition often treated in infancy.
• Bilateral choroid plexectomy is a surgical intervention for hydrocephalus.
• Ventriculoperitoneal shunts are used to manage hydrocephalus, but can fail.

Observation:

• A 5-year-old child with a history of bilateral choroid plexectomy for hydrocephalus presented with a failed ventriculoperitoneal shunt.
• The patient exhibited progressive ventriculomegaly at the time of the study.
• A ventricular perfusion technique was employed to assess cerebrospinal fluid (CSF) formation.

Findings:

• The calculated rate of CSF formation was 0.35 ml/min +/- 0.02 standard deviation.
• This rate of CSF production was determined to be within the normal range for the patient's age and condition.

Implications:

• The findings suggest that even in the presence of hydrocephalus and shunt failure, the choroid plexus may maintain normal CSF production rates.
• This information is crucial for understanding CSF dynamics in pediatric hydrocephalus patients.
• Further research may explore the relationship between CSF formation rates and treatment outcomes in similar cases.