Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A dosimetric leaf-setting strategy for shaping radiation fields using a multileaf collimator.

L Ma1, C Yu, M Sarfaraz

  • 1Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore 21201, USA.

Medical Physics
|June 7, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of donepezil treatment on cardiovascular mortality.

Clinical pharmacology and therapeutics·2010
Same author

Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody-drug conjugate SGN-75.

British journal of cancer·2010
Same author

Establishment and characterization of immortalized porcine hepatocytes for the study of hepatocyte xenotransplantation.

Transplantation proceedings·2010
Same author

Association of angiotensin-converting enzyme inhibitor-associated angioedema with transplant and immunosuppressant use.

Allergy·2010
Same author

Constructing defined chromosome segmental duplications in maize.

Cytogenetic and genome research·2010
Same author

Predicting the radiation exposure of terrestrial wildlife in the Chernobyl exclusion zone: an international comparison of approaches.

Journal of radiological protection : official journal of the Society for Radiological Protection·2010

A new dosimetric leaf-setting strategy for multileaf collimators (MLC) improves radiation field shaping. This method uses clinical dose criteria, unlike older geometric methods, reducing discrepancies and enhancing dose conformation.

Area of Science:

  • Medical Physics
  • Radiation Oncology

Background:

  • Current multileaf collimator (MLC) strategies rely on geometric criteria for radiation field shaping.
  • Geometric approaches may not fully optimize dose distribution for clinical targets.

Purpose of the Study:

  • To develop and evaluate a novel dosimetric leaf-setting strategy for MLCs.
  • To compare the dosimetric strategy against traditional geometric methods.

Main Methods:

  • Developed an iterative optimization algorithm to determine MLC leaf positions based on dosimetric criteria.
  • Created an empirical dose model to compare dosimetric and geometric leaf-setting strategies.
  • Analyzed differences in leaf positions and isodose lines.

Main Results:

Related Experiment Videos

  • The dosimetric leaf-setting strategy resulted in differences up to 0.5 cm in leaf positions and isodose lines compared to geometric methods.
  • This approach significantly reduces scalloping effects at the 50% isodose line, improving dose conformation.
  • The strategy separates leaf-setting from treatment planning, offering flexibility for vendors.

Conclusions:

  • A dosimetric leaf-setting strategy offers superior dose conformation compared to geometric methods.
  • This technique minimizes undesirable dose effects and streamlines the integration of MLC systems into treatment planning workflows.