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Measurement of urinary retinol binding protein by immunonephelometry
S J Twyman1, J Overton, D J Rowe
1Department of Chemical Pathology, Southampton General Hospital, SO16 6YD, Southampton, UK.
Abstract:
A method is described for the determination of retinol binding protein (RBP) by immunonephelometry. The assay is sensitive to 5 microg/l and has acceptable imprecision. The method correlates with an established ELISA assay. A provisional normal range is proposed for daytime random urine samples. The increased excretion of RBP in adult subject with type 1 diabetes mellitus is demonstrated.