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Updated: Aug 1, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
10:52

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence

Published on: December 23, 2022

Giant aneurysm following coil occlusion of patent ductus arteriosus

M Marasini1, A Rimini, L Zannini

  • 1Laboratory of Interventional Cardiology, Giannina Gaslini Institute, Children's Hospital, 16148 Genova,Italy. cardiologianvasiva@ospedale-gaslini.ge.it

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|June 8, 2000
PubMed

Insights

A giant aneurysm developed in an infant with Marfan syndrome after patent ductus arteriosus (PDA) coil occlusion. This rare complication highlights the need for careful pre- and post-procedure evaluation in these children.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Vascular Surgery

Background:

  • Marfan syndrome is a genetic disorder affecting connective tissue, potentially leading to cardiovascular complications.
  • Patent ductus arteriosus (PDA) is a congenital heart defect sometimes associated with Marfan syndrome.
  • Transcatheter coil occlusion is a common procedure for closing PDAs.

Observation:

  • A case report details a rare complication following PDA coil occlusion in an infant with Marfan syndrome.
  • A giant aneurysm developed at the site of the occluded PDA.
  • The infant had a confirmed diagnosis of Marfan syndrome.

Findings:

  • Successful coil occlusion of the PDA was achieved.
  • A significant and unexpected complication of giant aneurysm formation occurred post-procedure.
  • This complication is exceedingly rare in the context of PDA occlusion.

Implications:

  • The findings underscore the critical need for thorough pre-procedural assessment in pediatric patients with Marfan syndrome undergoing PDA occlusion.
  • Enhanced post-procedural surveillance is crucial to detect rare but severe complications like aneurysm formation.
  • This case may inform future guidelines for managing cardiovascular defects in Marfan syndrome patients.

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