Related Experiment Video
Updated: Aug 15, 2026

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
Published on: July 12, 2021
Demographic characteristics and risk factors of first febrile seizures: a Jordanian experience
F Abuekteish1, A S Daoud, M al-Sheyyab
1Department of Paediatrics, Faculty of Medicine, Jordan University and Science & Technology, Irbid, Jordan.
Insights
Aseptic meningitis occurred in 4% of children with first febrile seizures. Lumbar puncture is recommended for children under 2 with initial febrile seizures to rule out meningitis.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
Background:
- Febrile seizures are common in young children.
- Aseptic meningitis can present with febrile seizures.
- Early diagnosis and management are crucial.
Purpose of the Study:
- To investigate the incidence of aseptic meningitis in children with first febrile seizures.
- To identify risk factors and clinical characteristics associated with febrile seizures.
- To provide evidence-based recommendations for clinical practice.
Main Methods:
- Prospective study design.
- Inclusion of 203 children admitted with a first febrile seizure.
- Diagnostic workup including lumbar puncture for suspected meningitis.
Main Results:
- Aseptic meningitis diagnosed in 4% of cases.
- Mean age was 19.9 months, peak incidence between 6 months and 3 years.
- Upper respiratory tract infection was the most common trigger (53%).
Conclusions:
- Lumbar puncture should be considered in children under 2 years presenting with a first febrile seizure.
- Lower incidence of complex febrile seizures and sibling history noted compared to other studies.
- Highlights the importance of considering meningitis in the differential diagnosis.
Abstract:
A prospective study of 203 children admitted with a first febrile seizure was carried out over 18 months. Aseptic meningitis was diagnosed in nine children (4%). The mean age of the children was 19.9 months and the peak age incidence (88%) was between 6 months and 3 years. Complex seizures were seen in 16 cases (8%). There was a history of perinatal asphyxia in 16 patients (8%), positive family history of epilepsy in 3%, of first degree relatives and a history of febrile seizures in siblings in 13%. Upper respiratory tract infection was the commonest triggering factor, diagnosed in 53% of cases. The third child was the most commonly affected (22%) in the family. There was a lower incidence of both complex febrile seizures and history of seizures in siblings compared to other studies. Lumbar puncture should be considered for all children below the age of 2 years, presenting with a first febrile seizure.
Related Concept Videos
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Encephalitis l: Introduction
Seizures l: Introduction
Seizures ll: Types
Epilepsy ll: Types

