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Synthesis of FF-MAS from lithocholic acid
A Murray1, F C Grønvald, J K Nielsen
1Novo Nordisk A/S, Målov, Denmark.
Bioorganic & Medicinal Chemistry Letters
|June 8, 2000
Abstract:
An effective synthesis of 4,4 dimethyl-cholest-8,14,24-trien-3beta-ol (FF-MAS) from lithocholic acid is described, utilising a double oxidation and regioselective Wittig reaction as key steps.
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