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Related Experiment Videos

Mustard allergy in children.

F Rancé1, G Dutau, M Abbal

  • 1Hôpital des Enfants, Pneumologie-Allergologie, Toulouse, France.

Allergy
|June 8, 2000
PubMed
Summary

Mustard allergy often begins in early childhood, with symptoms like atopic dermatitis and urticaria. This study suggests including mustard in food allergy screenings for children.

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MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine.

Allergy·2011

Area of Science:

  • Pediatric Allergy
  • Clinical Immunology
  • Food Hypersensitivity

Background:

  • Mustard allergy is an under-recognized condition.
  • Limited data exists on its clinical presentation and diagnostic markers.
  • Associated allergies and sensitization patterns require further investigation.

Purpose of the Study:

  • To characterize the clinical features of mustard allergy in children.
  • To identify associated allergic conditions.
  • To define the diagnostic utility of skin prick tests (SPT), specific IgE, and oral food challenges.

Main Methods:

  • Investigated 36 children with positive mustard SPT.
  • Utilized open or single-blind, placebo-controlled food challenges (SBPCFC) for diagnosis.
  • Compared allergic children to 22 controls.

Main Results:

  • Common initial symptoms included atopic dermatitis (51.8%) and urticaria/angioedema (37%).
  • Allergic reactions often initiated before age 3 (53.3%).
  • Mean SPT wheal diameter was 8.8 mm; median sIgE was 14.8 kU/l; mean reactive dose was 153 mg.

Conclusions:

  • Mustard allergy reactions manifest early in life.
  • Clinical symptoms in children were generally not severe.
  • Mustard should be considered in pediatric food allergy screening protocols.

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