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Related Experiment Videos

Open-angle glaucoma associated with Graves disease.

K Ohtsuka1, Y Nakamura

  • 1Department of Ophthalmology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, Japan. kohtsuka@sapmed.ac.jp

American Journal of Ophthalmology
|June 14, 2000
PubMed
Summary

Graves disease patients show a higher prevalence of open-angle glaucoma and ocular hypertension. This includes normal-tension glaucoma, indicating a significant association between Graves disease and glaucoma development.

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Area of Science:

  • Ophthalmology
  • Endocrinology

Background:

  • Graves disease is an autoimmune disorder affecting the thyroid.
  • Glaucoma is a group of eye conditions that damage the optic nerve.

Purpose of the Study:

  • To determine the prevalence of open-angle glaucoma, including normal-tension glaucoma, in patients with Graves disease.

Main Methods:

  • A prospective study involving 104 Japanese patients with Graves disease.
  • Ophthalmic examinations included applanation tonometry, exophthalmometry, visual field perimetry, and orbital CT scans.

Main Results:

  • 13% of patients showed glaucomatous visual field defects without optic neuropathy.
  • 22% of patients were diagnosed with ocular hypertension (intraocular pressure > 21 mm Hg).

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  • Seven patients were diagnosed with normal-tension glaucoma.

    • Conclusions:

    • The prevalence of open-angle glaucoma, normal-tension glaucoma, and ocular hypertension is significantly elevated in Graves disease patients compared to the general population.