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Induction of CD44 expression in stab wounds of the brain: long term persistence of CD44 expression
S S Stylli1, A H Kaye, U Novak
1Department of Neurosurgery, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.
Abstract:
We studied the expression of the hyaluronan receptor protein CD44 in the mouse brain in response to stab injuries. CD44 expression was strongly activated in the area surrounding the injury within 2 days and then persisted for over 2 months. The expression extended in a direct line the depth of the actual wound inflicted. It appears that CD44 may be involved in the wound healing processes following injury to the brain.
