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Multiple meningiomas: case report and review of the literature
A Granger1, R Sainsbury, T Wilkinson
1Department of Health Care of the Elderly, The Princess Margaret Hospital, Christchurch, New Zealand.
Abstract:
A case of a 69 year old woman with multiple meningiomas is presented. Since her first presentation with Jacksonian seizures in 1978, she has had 16 meningiomas excised in seven separate surgical procedures. This is extremely unusual due to both the large number of tumours, and the long period over which they have occurred. We review the epidemiology, possible pathogenesis and genetic associations of this condition.
Insights
This case study details a 69-year-old woman with multiple meningiomas, experiencing 16 tumor excisions over 40 years. The study reviews the epidemiology, pathogenesis, and genetic links of this rare condition.
Area of Science:
- Neurosurgery
- Oncology
- Genetics
Background:
- Multiple meningiomas are rare intracranial tumors.
- This case presents an exceptionally high number of meningiomas over an extended period.
Observation:
- A 69-year-old woman presented with Jacksonian seizures in 1978.
- She underwent seven surgical procedures for the excision of 16 meningiomas.
Findings:
- The patient's history of multiple meningiomas is highly unusual.
- Review of epidemiology, pathogenesis, and genetic associations is presented.
Implications:
- This case highlights the importance of long-term monitoring for patients with multiple meningiomas.
- Further research into the genetic factors may improve understanding and treatment of this condition.