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Recurrent urinary tract infections and genitourinary tract abnormalities in the Imerslund-Gräsbeck syndrome
C Sandoval1, P Bolten, I Franco
1Department of Pediatrics, New York Medical College, Valhalla 10595, USA.
Abstract:
Two Imerslund-Gräsbeck patients who presented with recurrent urinary tract infections and genitourinary abnormalities are described. The patients were evaluated with abdominal ultrasounds, voiding cystourethrograms, and Schilling tests. Each patient had large postvoid residual urine secondary to a motor-neurogenic bladder. One had a duplication of the distal urethra manifesting as two meatal openings. There was lack of urinary excretion of radioactive vitamin B12 on Schilling tests in both patients. Patients with Imerslund-Gräsbeck syndrome may be predisposed to urinary tract infections because of incomplete bladder emptying. Complete physical and radiological examinations of the genitourinary tract should be performed.
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