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Published on: July 24, 2016
MR imaging of herpes simplex type 1 encephalitis in infants and young children: a separate pattern of findings
J R Leonard1, C J Moran, D T Cross
1Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.
Objective:
We sought to identify the initial MR findings of herpes simplex encephalitis in infants and young children.
Conclusion:
MR imaging findings of herpes encephalitis in infants and young children appear to differ from those seen in neonates, older children, and adults. Appreciation of this MR imaging pattern coupled with a strong clinical suspicion of herpes helps to ensure the correct diagnosis is made.
Insights
Initial magnetic resonance (MR) imaging findings for herpes simplex encephalitis in infants and young children differ from other age groups. Recognizing this unique MR pattern aids in timely herpes encephalitis diagnosis.
Area of Science:
- Neurology
- Pediatric Radiology
- Infectious Diseases
Background:
- Herpes simplex encephalitis (HSE) is a severe neurological infection.
- Magnetic resonance (MR) imaging is crucial for diagnosing HSE.
- HSE presentation on MR imaging can vary by age.
Purpose of the Study:
- To characterize the initial MR imaging findings of HSE in infants and young children.
- To differentiate HSE imaging patterns in this specific age group.
Main Methods:
- Retrospective review of MR imaging studies in infants and young children diagnosed with HSE.
- Analysis of lesion location, signal intensity, and enhancement patterns.
Main Results:
- MR imaging findings in infants and young children with HSE show distinct patterns.
- These patterns differ from those observed in neonates, older children, and adults.
Conclusions:
- The MR imaging appearance of HSE in infants and young children is unique.
- Awareness of these specific MR findings, alongside clinical suspicion, improves diagnostic accuracy for HSE.
Related Concept Videos
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
Viral Meningitis
Herpes
Arboviral Encephalitis

