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Medical abortion in China.
S Wu1
1National Research Institute for Family Planning, Beijing.
Summary
Early medical abortion in China, using mifepristone and misoprostol, demonstrates high success rates (90-97%) with minimal complications. This method is a safe and accepted alternative to surgical abortion when medically supervised.
Area of Science:
- Reproductive Health
- Pharmacology
- Obstetrics & Gynecology
Background:
- Mifepristone, approved in China in 1986, is used for early pregnancy termination.
- Established regimens involve specific dosages of mifepristone and misoprostol.
- Medical abortion is increasingly recognized as a viable alternative to surgical procedures.
Purpose of the Study:
- To review the literature on the efficacy and safety of early medical abortion in China.
- To summarize commonly used drug regimens and their outcomes.
- To identify key complications and management strategies.
Main Methods:
- Literature review of studies on medical abortion in China.
- Analysis of data on mifepristone and misoprostol regimens.
- Evaluation of reported success rates, complications, and patient acceptance.
Main Results:
- Complete abortion rates range from 90% to 97%.
- Regimens include 150 mg mifepristone (divided doses) or 200 mg (single dose), followed by misoprostol.
- Complications like emergency curettage (<1% to 4%) and blood transfusion (<1%) are low; ectopic pregnancy is a primary concern.
Conclusions:
- Medical abortion in China is highly effective and well-accepted.
- Ultrasound is crucial for ruling out ectopic pregnancy.
- Supervision and monitoring are essential for safe and effective medical abortion.