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Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
[Open heart surgery in three patients receiving dialysis for more than 20 years]
T Ishida1, H Nishida, Y Tomizawa
1Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical University, Japan.
Insights
Open heart surgery is feasible for long-term hemodialysis (HD) patients, even those with over 20 years on HD. Arterial grafts are recommended for coronary artery bypass grafting (CABG) in HD patients, with careful post-transplant management for kidney recipients.
Area of Science:
- Cardiovascular Surgery
- Nephrology
- Transplantation
Background:
- The number of patients on chronic hemodialysis (HD) is rising in Japan, with a significant population exceeding 20 years on HD.
- Open heart surgery in patients with long-term HD is uncommon and presents unique management challenges.
Observation:
- Our institute has performed 135 open heart surgeries on HD patients, including 92 coronary artery bypass grafting (CABG) and 43 other procedures.
- Three cases of open heart surgery were successfully performed on patients with over 20 years of HD history, including complex CABG and valve replacement procedures.
Findings:
- All three patients with extended HD histories were discharged with patent grafts after surgery.
- Aggressive use of arterial conduits for revascularization is advised for CABG in HD patients.
- Post-kidney transplantation patients require meticulous management to prevent graft dysfunction and rejection.
Implications:
- This study suggests that open heart surgery can be safely performed in select long-term HD patients.
- The findings support the use of arterial grafts for improved outcomes in CABG for HD patients.
- Careful perioperative and postoperative management is crucial for successful outcomes in this complex patient group.
Abstract:
In Japan, the number of chronic hemodialysis (HD) patients is increasing, and there are 7,000 cases with a more than 20 year history of HD. At our institute, we have experienced 135 cases of open heart surgery in patients on HD, including 92 isolated CABG cases and 43 other open heart surgery cases. However, open heart surgery for patients with a more than 20 year history on HD is rare. Open heart surgery on HD patients is rather difficult, since perioperative management can be complicated and special care must be taken for prophylaxis of infection, fluid and electrolyte management and anticoagulation therapy. Many complications have been published in HD patients. At our institute, 3 cases of open heart surgery in patients with more than a 20 year history of HD have been performed. These included triple CABG, double CABG + AVR and double CABG in a post-kidney transplantation patient. They were discharged uneventfully with angiographically patent grafts. It is concluded that for CABG in patients on HD, aggressive use of arterial conduits for revascularization is recommended. For patients with a transplanted kidney, careful management against dysfunction and rejection is necessary.
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