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[Neurally mediated syncope in association with small cell lung carcinoma]
Y Demura1, S Mizuno, M Wakabayashi
1Third Department of Internal Medicine, Fukui Medical University.
Summary
A 66-year-old woman experienced frequent fainting spells due to neurally mediated syncope. Cancer treatment for small cell lung carcinoma successfully resolved these syncopal episodes, highlighting an unusual association.
Area of Science:
- Cardiology
- Neurology
- Oncology
Background:
- Small cell lung carcinoma (SCLC) is an aggressive form of lung cancer.
- Neurally mediated syncope (NMS) is characterized by transient loss of consciousness due to autonomic nervous system dysfunction.
Observation:
- A 66-year-old female patient presented with recurrent syncopal episodes.
- The patient was concurrently undergoing treatment for small cell lung carcinoma.
Findings:
- Head-up tilt table testing confirmed neurally mediated syncope, inducing severe hypotension within 12 minutes at an 80-degree tilt.
- Chemotherapy and radiotherapy for SCLC led to the complete resolution of syncopal episodes.
Implications:
- This case suggests a potential link between small cell lung carcinoma and neurally mediated syncope.
- Effective cancer treatment may resolve associated autonomic dysfunction, offering a novel therapeutic insight.