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Failed adoptive immunity transfer: reactivation or reinfection?
Journal of Viral Hepatitis
|June 10, 2000
Summary
Hepatitis B virus (HBV) reactivation occurred in a bone marrow transplant recipient despite initial HBsAg negativity. PCR confirmed HBV infection in both patient and donor, highlighting PCR
Area of Science:
- Hepatology
- Virology
- Immunology
Background:
- Hepatitis B virus (HBV) infection poses risks in immunocompromised patients, including bone marrow transplant (BMT) recipients.
- Assessing HBV status in donors and recipients is crucial for managing post-transplant complications.
- Serological markers and molecular assays play distinct roles in diagnosing active HBV infection.