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Updated: Aug 9, 2026

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
Published on: June 26, 2013
Coregistration of brain single-positron emission computed tomography and magnetic resonance images using anatomical
L Ferrari de Oliveira1, P M Azevedo Marques
1School of Engineering of São Carlos, University of São Paulo, Brazil. lferrari@cci.fmrp.usp.br
Abstract:
The present report describes a computer tool for the coregistration of single-positron emission computed tomography (SPECT) and magnetic resonance (MR) images to aid the diagnosis. Two types of images are used for some neurologic diseases: one of them anatomic (magnetic resonance) and the other metabolic (SPECT), with the specialist being required to make a mental integration of the examinations. This procedure can be improved by using a computer tool that might permit the presentation of this information in a single image. The coregistration is performed on the basis of pairs of points positioned by a specialist according to the structures present in the images and the least squares error is calculated between them using Euclidean distance. Coinciding planes and section thickness are selected for the two modalities and the SPECT image is processed so as to have the same spatial resolution as the resonance image.
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Magnetic Resonance Imaging
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These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

