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A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
10:10

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail

Published on: February 3, 2016

[Infected arteriovenous fistulae for hemodialysis]

P Bachleda1, P Utíkal, J Zadrazil

  • 1I. chirurgická a III. interní klinika FN, Olomouc

Bratislavske Lekarske Listy
|June 10, 2000
PubMed

Insights

Infectious complications are more frequent with expanded polytetrafluoroethylene (ePTFE) grafts than autogenous fistulae for hemodialysis access. Early infections were rare, but late infections highlight risks associated with ePTFE grafts.

Area of Science:

  • Nephrology
  • Vascular Surgery
  • Infectious Diseases

Context:

  • Hemodialysis requires reliable vascular access, with angioaccess procedures being crucial.
  • Infectious complications pose a significant risk to patients undergoing hemodialysis.
  • A 12-year retrospective review was conducted to evaluate angioaccess procedure outcomes.

Purpose:

  • To determine the frequency of infectious complications following angioaccess procedures for hemodialysis.
  • To compare infection rates between autogenous fistulae and expanded polytetrafluoroethylene (ePTFE) grafts.

Summary:

  • A total of 571 angioaccess procedures were reviewed, including 88 ePTFE grafts.
  • Early infectious complications were infrequent and primarily observed in autogenous fistulae.
  • Late infectious complications occurred in 2.3% of autogenous fistulae and 7.95% of ePTFE grafts.

Impact:

  • Infected arteriovenous fistulae can lead to severe complications such as thrombosis, bleeding, aneurysm, and sepsis.
  • Surgical repair is often necessary for infected arteriovenous fistulae.
  • Findings emphasize the differential risk of infection between graft types, informing clinical practice and patient selection.

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