[Use of sulperazone in acute surgical conditions]

In the period between February 2, 1988 and October 30, 1998, the investigators administered Sulperazon to 20 patients at the Surgery Department 1, University Hospital Olomouc, in whom they expected good clinical effect (i.e., high concentration in bill, effect on respiratory tract pathogens). Sulperazon was administered in 12 cases as a drug of first choice, in 8 cases as a drug of second choice. In all cases, relief from clinical symptoms of infection was observed within 5 days of treatment and in 83% of cases eradication of previously cultivated pathogen was achieved. Sulperazon was well tolerated and no side effects or impoivment of laboratory test were observed. In 4 cases, prolonged administration was complicated by candida superinfection. Sulperazon proved to be effective in surgery in treatment of infectious complications of bile duct and pancreas diseases and in thoracic cavity pathology.