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Experimental Metastasis and CTL Adoptive Transfer Immunotherapy Mouse Model
Published on: November 26, 2010
Metastatic microcystic adnexal carcinoma in an immunocompromised patient
P Carroll1, G D Goldstein, C W Brown
1Department of Internal Medicine, University of Kansas Medical Center, Lawrence, Kansas, USA.
Background:
Microcystic adnexal carcinoma is an uncommon, locally aggressive cutaneous neoplasm. To date, there are only two reports of histologically proven lymph node involvement with this tumor. We describe a case of a patient with microcystic adnexal carcinoma who developed multiple local metastasis in transit with histologically proven lymph node involvement and was diagnosed with chronic lymphocytic leukemia.
Objective:
To describe the details of our case and to review what is currently known about this tumor.
Methods:
Mohs micrographic surgery was utilized for tumor removal.
Results:
This patient developed multiple tumors of the scalp over the period of a 1 year which were histologically proven to be microcystic adnexal carcinoma. All tumors were noncontiguous and presented on the scalp. During the histologic analysis of the last tumor removed by Mohs micrographic surgery a lymph node was resected which revealed infiltrative microcystic adnexal carcinoma.
Conclusions:
We present the case of an immunocompromised patient treated for microcystic adnexal carcinoma with Mohs micrographic surgery who proceeded to develop local metastasis in transit.
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