[Antimycotic antibiotics (author's transl)]

Area of Science:

• Pharmacology
• Mycology
• Infectious Diseases

Background:

• Antibiotics with antimycotic activity are crucial for treating fungal infections.
• Understanding their properties is essential for effective clinical application.

Purpose of the Study:

• To review selected antibiotics with antimycotic action.
• To provide a comprehensive overview of their characteristics and applications.

Main Methods:

• Literature review of scientific articles and drug information.
• Comparative analysis of physicochemical and pharmacotoxicological properties.
• Discussion of antifungal spectrum, mechanisms, dosage, and preparations.

Main Results:

• Griseofulvin, amphotericin-B, natamycin, nystatin, and pecilocin exhibit distinct antimycotic properties.
• Detailed information on their properties, range, mechanisms, dosage, and formulations is presented.

Conclusions:

• This review consolidates essential data on key antifungal antibiotics.
• It serves as a reference for clinicians and researchers in antifungal therapy.