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Detection of lectins in the nuclear matrix of nerve tissue cells
R G Akhalkatsi1, L O Kharazishvili, T V Bolotashvili
1Department of Biochemistry and Biotechnology, Javakhishvili Tbilisi State University, Tbilisi, Georgia. cell@biomed.viamnet.edu.ge
Biochemistry. Biokhimiia
|June 13, 2000
Abstract:
Lectins have been detected in the nuclear matrix of nerve tissue cells, and an extraction procedure for the protein fraction with lectin activity has been developed. The lectins are characterized by hemagglutinating activity that is inhibited by D-GlcNAc, D-Gal, Lac, and D-Glc. The existence of lectins with similar molecular masses (from 7 to 20 kD) in the nuclear matrix of calf and rat brain has been shown.