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Updated: Aug 10, 2026

The Use of Chemostats in Microbial Systems Biology
Published on: October 14, 2013
Microbial physiological state at low growth rate in natural and engineered ecosystems
1Department of Biological Sciences, Purdue University, Lilly Hall of Life Sciences, West Lafayette, IN 47907-1392, USA. akonopka@bilbo.bio.purdue.edu
Abstract:
Microbes often grow in nature and bioreactors at very low growth rates. However, the physiological consequences at low growth rates have not been explored as completely as at faster growth rates or under starvation conditions. Nutrient flux to (and through) the cell surface and non-growth-dependent energy consumption (maintenance) are important considerations under these conditions. The biomass recycle reactor is a system to explore physiological state at low growth rate, and to optimize certain industrial process rates.
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