PSA Control Following Definitive Therapy for Clinically Localized Prostate Cancer

The two goals of treatment for clinically localized prostate cancer are disease control and a good quality of life. At present, the options are radical surgery, conformal or conventional external-beam radiation, and interstitial radiation. This article reviews the effectiveness of these techniques, as judged by serum prostate specific antigen monitoring, with special emphasis on magnetic resonance-guided interstitial brachytherapy.