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Updated: Jul 22, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

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Management issues in chordoma: a case series.

P T Tai¹, P Craighead, S K Liem

¹Allan Blair Cancer Centre, Regina, SK, Canada.

Clinical Oncology (Royal College of Radiologists (Great Britain))

|June 15, 2000

Summary

This case series highlights challenges in diagnosing and managing chordomas, rare bone tumors. Early detection and combined surgical and radiotherapy approaches are crucial for better patient outcomes.

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Area of Science:

Oncology
Neurosurgery
Radiation Oncology

Background:

Chordomas are rare, slow-growing bone tumors originating from notochordal remnants.
This study reviews 27 cases of chordoma managed across two Canadian institutions between 1954 and 1998.

Observation:

Diagnostic challenges, including subtle early-stage presentations, are discussed.
One case highlights incidental diagnosis via computed tomography (CT) scan following trauma.
Magnetic resonance imaging (MRI) proved valuable for surgical and radiotherapy planning.

Findings:

A combined surgical and radiotherapy approach is supported by literature review and case series findings.
Management of recurrent chordomas requires careful consideration.
High index of suspicion is necessary for early chordoma diagnosis.

Implications:

Improved diagnostic strategies are needed to identify chordomas earlier.
Optimized treatment planning using advanced imaging like MRI can enhance therapeutic efficacy.
Multidisciplinary management involving surgery and radiotherapy is essential for chordoma treatment.