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Von Willebrand's disease--a potential bleeding problem in plastic surgery
Plastic and Reconstructive Surgery
|September 1, 1976
Summary
Von Willebrand disease, a hereditary bleeding disorder, can cause unexpected bleeding during or after surgery. Patients with this condition are particularly prone to prolonged bleeding times after taking aspirin.
Area of Science:
- Hematology
- Genetics
Background:
- Von Willebrand disease is a prevalent hereditary bleeding disorder.
- It can lead to significant intraoperative or postoperative hemorrhage.
Observation:
- Clinical suspicion is key for diagnosis.
- Laboratory investigations are crucial for confirmation.
Findings:
- Patients with Von Willebrand disease exhibit heightened susceptibility to bleeding time prolongation.
- Aspirin ingestion exacerbates this susceptibility.
Implications:
- Early diagnosis and management are vital for surgical patients.
- Awareness of aspirin's effect is critical for managing bleeding risk.