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[Sweet syndrome in an infant]
Insights
Acute febrile neutrophilic dermatosis, or Sweet's syndrome, is rare in infants. This case highlights a corticosteroid-resistant presentation and its spontaneous evolution, offering insights into infantile Sweet's syndrome.
Area of Science:
- Pediatric Dermatology
- Rare Infantile Diseases
Background:
- Acute febrile neutrophilic dermatosis (Sweet's syndrome) is a rare condition in infants.
- Systemic corticosteroid therapy is the conventional treatment, typically yielding rapid clinical improvement.
Observation:
- A seven-month-old infant presented with a ten-day history of rash and fever.
- Diagnosis of Sweet's syndrome was confirmed via physical examination and skin biopsy.
- Systemic corticotherapy demonstrated limited efficacy in this infant.
Findings:
- This case presents a corticosteroid-resistant form of Sweet's syndrome in infancy.
- The study documents the clinical and biological characteristics of infantile Sweet's syndrome.
- Observation of the disease's spontaneous course provides unique insights.
Implications:
- Highlights the variability of Sweet's syndrome presentation and treatment response in infants.
- Emphasizes the need for considering alternative management strategies for resistant cases.
- Contributes to understanding the natural history of infantile Sweet's syndrome.
Background:
Acute febrile neutrophilic dermatosis (Sweet's syndrome) is very uncommon in infancy. Systemic corticosteroid treatment is the standard therapy, usually leading to dramatic improvement within a few days.
Case Report:
A seven-month-old female infant was admitted for investigation of a rash developing over ten days with fever. Physical examination and skin biopsy led to a diagnosis of Sweet's syndrome. The relative inefficiency of systemic corticotherapy induced the parents to stop all treatment.
Conclusion:
This case report allows us: 1) to consider the clinical and biological features of Sweet's syndrome in infancy; 2) to describe a corticosteroid resistant disease; and 3) to observe the course of a spontaneous evolution of Sweet's syndrome.