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11:54
Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
Published on: January 21, 2018
Complications of allergic rhinitis
1Department of Allergy and Immunology, Children's Hospital of Pittsburgh, Pittsburgh, PA 15213, USA.
The Journal of Allergy and Clinical Immunology
|June 16, 2000
Summary
Allergic rhinitis often leads to respiratory issues like asthma and sinusitis. Treating nasal allergies may prevent recurrent ear infections and improve treatment outcomes.
Area of Science:
- Otolaryngology
- Allergy Immunology
Background:
- Allergic rhinitis is closely associated with upper and lower respiratory diseases.
- Epidemiologic evidence supports the link between nasal allergies and conditions such as asthma, sinusitis, and otitis media with effusion.
Purpose of the Study:
- To explore the pathophysiologic links between allergic rhinitis and sinusitis/otitis media with effusion.
- To highlight the role of inflammation in the development of these conditions.
- To emphasize the potential benefits of diagnosing and treating nasal allergies in patients with otitis media with effusion.
Main Methods:
- Review of existing epidemiologic evidence and proposed pathophysiologic models.
- Investigation into the roles of viruses and allergens in otitis media with effusion development.
Main Results:
- Inflammation from nasal allergy and/or viral infection can lead to obstruction, fluid accumulation, and acute or chronic disease.
- Untreated conditions can result in mucosal damage and chronic inflammation, obstruction, and infection.
Conclusions:
- Diagnosing and treating nasal allergies may prevent recurrent episodes of otitis media with effusion.
- Prophylactic treatment of nasal allergies can improve therapeutic responses in patients with related respiratory conditions.
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