[Penile-perineal-scrotal gangrene. Epidemiologic, diagnostic, and therapeutic features. Report of 32 cases]

The authors analyse the epidemiological, diagnostic and therapeutic aspects of peno-perineo-scrotal gangrene in the urology department of a university hospital of a developing African country. The frequency of this disease is low, four cases per year, and most patients (about 72%) are between the ages of 40 to 70 years. The authors identified urethral stricture (31.25%) and idiopathic causes as the main predisposing factors, and many pathogenic bacteria, including P. mirabilis, P. aeruginosa, S. aureus, K. pneumoniae etc., as decisive factors. The treatment of peno-perineo-scrotal gangrene must be both medical and surgical. In addition to the medical treatment currently performed in the department, the authors would like to combine hyperbaric oxygen therapy and, as in Japan, the use of argatroban to accelerate wound healing.