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[Takayasu's arteritis].

G Parisi, A R Gobbini, G Vedovini

    Minerva Medica
    |June 20, 2000
    PubMed
    Summary
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    Takayasu's Arteritis (TA) is a widespread condition affecting the aorta and its branches globally, not just young women of Japanese origin. This review details its diverse presentations and diagnostic criteria.

    Area of Science:

    • Vascular Medicine
    • Rheumatology
    • Immunology

    Context:

    • Takayasu's Arteritis (TA) is a rare, chronic inflammatory condition affecting large arteries, primarily the aorta and its branches.
    • Historically, TA was considered uncommon and primarily affected young women of Japanese descent.
    • Recent evidence suggests a broader global prevalence and varied clinical manifestations.

    Purpose:

    • To review the ethiopathogenetic mechanisms and pathological patterns of vascular damage in Takayasu's Arteritis.
    • To highlight the worldwide distribution and diverse clinical and angiographic presentations of TA.
    • To discuss updated diagnostic criteria for Takayasu's Arteritis.

    Summary:

    • Takayasu's Arteritis (TA) is a chronic granulomatous arteritis impacting the aorta and its major branches.

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  • The review covers ethiopathogenetic mechanisms and pathological vascular damage.
  • TA is globally prevalent across all ages, with distinct Japanese (aortic arch) and Indian (abdominal aorta/renal arteries) forms, presenting varied clinical and angiographic features.

    • Impact:

    • Broadens the understanding of Takayasu's Arteritis prevalence beyond traditional demographics.
    • Emphasizes the need for global awareness and recognition of TA's diverse manifestations.
    • Underscores the importance of updated diagnostic criteria for accurate TA identification and management.