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New antiarrhythmic agents: a conceptually novel approach
1Institute of Organic Chemistry, Semmelweis University, Budapest, H-1092, Högyes u. 7, Hungary. matypet@szerves.sote.hu
Medicinal Research Reviews
|June 22, 2000
Abstract:
Synthesis and biological evaluation of novel phenoxyalkyl amines exhibiting both class Ib and class III type electrophysiological properties are described. Two compounds showed excellent antiarrhythmic effects against reperfusion induced arrhythmias.