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Metabolic syndrome X: a review
The Canadian Journal of Cardiology
|June 23, 2000
Summary
Metabolic syndrome X, common in industrialized nations, involves insulin resistance, obesity, and hypertension. Early diagnosis and treatment are crucial due to its association with increased cardiovascular events.
Area of Science:
- Endocrinology and Metabolism
- Cardiovascular Disease Risk Factors
Background:
- Metabolic syndrome X is a prevalent condition characterized by a cluster of risk factors.
- It affects a significant portion of the adult population in industrialized countries, with higher prevalence in men.
Purpose of the Study:
- To review current knowledge on the abnormalities associated with metabolic syndrome X.
- To discuss diagnostic criteria and therapeutic targets for managing this complex syndrome.
Main Methods:
- This is a review article, summarizing existing research and clinical knowledge.
- It examines individual risk factors and their interrelationships within the syndrome.
Main Results:
- Metabolic syndrome X is linked to insulin resistance, hyperinsulinemia, dyslipidemia, hypertension, and abdominal obesity.
- Associated conditions include noninsulin-dependent diabetes mellitus, increased cardiovascular event risk, and abnormalities in blood coagulation, hyperuricemia, and microalbuminuria.
Conclusions:
- Patients with metabolic syndrome X exhibit a clustering of cardiac risk factors.
- Special attention to diagnosis and treatment is warranted for individuals with this syndrome to mitigate cardiovascular risks.