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Cutaneous deciduosis.
K P Fair1, J W Patterson, R J Murphy
1Departments of Pathology and Dermatology, University of Virginia Health Science Center, Charlottesville 22908-0214, USA.
Journal of the American Academy of Dermatology
|June 23, 2000
Summary
Cutaneous deciduosis, a rare endometriosis manifestation, can mimic cancer. This study details two new cases, including an unusual vulvar presentation, highlighting diagnostic challenges.
Area of Science:
- Gynecologic Pathology
- Dermatopathology
Background:
- Cutaneous deciduosis is a rare form of endometriosis.
- It is often misdiagnosed as malignancy.
- Previously, it was only reported in surgical scars.
Observation:
- Two new cases of cutaneous deciduosis are presented.
- One occurred in a pregnant woman as a vulvar papule, an unprecedented location.
- The second case involved an umbilical nodule found during a cesarean section.
Findings:
- Histology revealed atypical large cells with edema and inflammation in the vulvar case.
- Immunohistochemistry showed vimentin and Ki-1 (CD30) positivity.
- The umbilical nodule displayed multilobulated intradermal nodules composed of epithelioid cells.
Implications:
- The varied histology presents diagnostic difficulties.
- Clinical recognition is challenging without a suggestive history or location.
- This expands the known clinical and histological spectrum of cutaneous deciduosis.
