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Respiratory emergencies.
R Aurora1, F Milite, N J Vander Els
1Department of Medicine, Memorial Sloan-Kettering Cancer Center and Cornell University Medical College, New York, NY 10021, USA.
Seminars in Oncology
|June 23, 2000
Summary
Respiratory emergencies arise from airway, vascular, or lung diseases. Bronchoscopic therapies, imaging, and prophylaxis offer management options for conditions like airway obstruction, superior vena cava syndrome, and Pneumocystis pneumonia.
Area of Science:
- Pulmonology and critical care medicine.
- Interventional pulmonology.
- Thoracic oncology.
Background:
- Respiratory emergencies stem from diverse pathologies affecting airways, thoracic vessels, and lung parenchyma.
- Conditions range from common asthma to life-threatening pulmonary embolism and superior vena cava syndrome.
- Neoplastic and infectious etiologies, including Pneumocystis pneumonia in cancer patients, contribute significantly to respiratory distress.
Purpose of the Study:
- To review current diagnostic and therapeutic approaches for various respiratory emergencies.
- To highlight the role of bronchoscopic interventions in managing airway obstruction.
- To discuss the diagnostic utility of imaging modalities and the importance of prophylaxis.
Main Methods:
- Literature review of conditions causing respiratory emergencies.
- Discussion of bronchoscopic therapies such as laser ablation, photodynamic therapy (PDT), and stent placement.
- Overview of diagnostic tools including spiral computed tomography (CT) and ventilation perfusion scintigraphy.
Main Results:
- Airway obstruction can be effectively managed with bronchoscopic interventions.
- Superior vena cava syndrome is frequently associated with bronchogenic carcinoma and lymphoma.
- Pneumocystis carinii pneumonia (PCP) incidence is rising in cancer patients, but preventable with prophylaxis.
- Adult respiratory distress syndrome (ARDS) treatment remains challenging with poor prognosis.
Conclusions:
- A multi-faceted approach involving diagnostics, interventional procedures, and preventative measures is crucial for managing respiratory emergencies.
- Early diagnosis and targeted therapies, including bronchoscopy, improve outcomes for specific conditions.
- Despite advances, certain severe respiratory conditions like ARDS continue to pose significant challenges.