Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Compodock, a new device for sterile docking.

P F van Der Meer1, F T Biekart, R N Pietersz

  • 1Blood Bank North Holland, Amsterdam, The Netherlands.

Transfusion
|June 24, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vox Sanguinis International Forum on platelet cryopreservation.

Vox sanguinis·2017
Same author

Vox Sanguinis International Forum on platelet cryopreservation: Summary.

Vox sanguinis·2017
Same author

HBsAg loss after peginterferon-nucleotide combination treatment in chronic hepatitis B patients: 5 years of follow-up.

Journal of viral hepatitis·2017
Same author

Comparison of haemostatic function of PAS-C-platelets vs. plasma-platelets in reconstituted whole blood using impedance aggregometry and thromboelastography.

Vox sanguinis·2017
Same author

Serum eye drops: a survey of international production methods.

Vox sanguinis·2017
Same author

Alternatives in blood operations when choosing non-DEHP bags.

Vox sanguinis·2017

The Compodock device successfully maintained sterility in medical tubing connections, even with heavy bacterial contamination. It meets ISO standards for tensile strength and is suitable for blood bank use.

Area of Science:

  • Medical Device Technology
  • Sterilization and Aseptic Techniques
  • Biotechnology

Background:

  • A novel sterile docking device, Compodock, was developed to connect PVC tubing for medical applications.
  • The device aims to maintain system sterility during the connection process.

Purpose of the Study:

  • To evaluate the sterility assurance of the Compodock device.
  • To assess the mechanical integrity (tensile strength) of Compodock connections.
  • To determine the user-friendliness and processing time of the Compodock system.

Main Methods:

  • Sterility was tested by welding tubing contaminated with Bacillus subtilis spores and aerosols, in both dry and liquid-filled conditions.
  • Bacterial cultures were performed on welded areas to assess microbial growth.

Related Experiment Videos

  • Tensile strength was measured according to ISO 3826 standards.
  • User-friendliness and speed were evaluated under semi-routine conditions.

    • Main Results:

    • No bacterial growth was observed in any cultures from welded tubing, regardless of contamination type (exterior or aerosol) or tubing condition (dry or wet).
    • Tensile strength of the welds met or exceeded ISO 3826 standards, with mean maximal strength between 73-100 N.
    • Compodock demonstrated good user-friendliness, with easy weld opening, clear instructions, and an average processing time of 52 seconds.

    Conclusions:

    • The Compodock device effectively maintains a functionally closed system and sterility, even under significant bacterial contamination.
    • Connection integrity meets established ISO standards.
    • The Compodock is a suitable and reliable device for routine implementation in blood bank settings.