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Intracardiac lymphoma in a child: successful treatment with chemotherapy alone
1Department of Pediatrics, University of Chicago Children's Hospital, 5839 S. Maryland Avenue, Chicago, IL 60637, USA.
Insights
A pediatric patient with non-Hodgkin's lymphoma experienced cardiac symptoms due to large tumor masses. Chemotherapy successfully resolved these cardiac tumors without surgery.
Area of Science:
- Pediatric Oncology
- Cardiology
- Hematology
Background:
- Non-Hodgkin's lymphoma (NHL) is a significant diagnosis in pediatric patients.
- Cardiac involvement in pediatric NHL is rare but can lead to severe complications.
- Early detection and management are crucial for improving outcomes.
Observation:
- A 5-year-old female with a history of NHL presented with cough and palpitations.
- Physical examination revealed a characteristic cardiac tumor plop.
- Electrocardiogram (ECG) showed paroxysmal supraventricular tachycardia.
Findings:
- Transthoracic echocardiogram identified multiple large tumor masses in both the right and left atria.
- The right atrial tumor exhibited significant mobility, prolapsing through the tricuspid valve orifice.
- Complete resolution of cardiac tumors was achieved with chemotherapy, obviating the need for surgical intervention.
Implications:
- This case highlights the potential for cardiac infiltration in pediatric NHL.
- Chemotherapy alone can be an effective treatment for cardiac tumors secondary to NHL.
- Non-invasive management strategies should be considered in similar pediatric cases.
Abstract:
A 5-year-old female child with history of non-Hodgkin's lymphoma presented with cough and palpitation. On physical examination a cardiac tumor plop was heard. Paroxysmal supraventricular tachycardia was noted on the electrocardiogram. Transthoracic echocardiogram revealed multiple large tumor masses within the right and the left atrium. The right atrial tumor was flopping back and forth at the tricuspid valve orifice. The tumor resolved completely with chemotherapy without any surgical intervention.