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Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists
B L Chenard1, F S Menniti, M J Pagnozzi
1Central Research Division, Pfizer Inc., Groton, CT 06340, USA. chenab@pfizer.com
Bioorganic & Medicinal Chemistry Letters
|June 24, 2000
Abstract:
Quinazolin-4-one derivatives of methaqualone substituted at C-2 define a new class of noncompetitive antagonists at AMPA receptors.
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