Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Immunotherapy in non-allergic diseases].

¹Unidad de Alergología, Hospital Valle Hebrón, Barcelona, España.

Allergologia Et Immunopathologia

|June 27, 2000

Summary

Advances in understanding immunological diseases like primary immunodeficiencies (PID) and autoimmune diseases have led to improved therapies. Treatments such as immunoglobulin replacement and cell transplantation significantly enhance patient outcomes and quality of life.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Outcomes of splenectomy in patients with common variable immunodeficiency (CVID): a survey of 45 patients.

Clinical and experimental immunology·2013

Same author

Diagnosis of autosomal-dominant hyperimmunoglobulin E syndrome.

Journal of investigational allergology & clinical immunology·2012

Same author

[Spanish Paediatric Infectious Diseases Society consensus document on the treatment of fungal infections based on the immune response].

Anales de pediatria (Barcelona, Spain : 2003)·2010

Same author

A multi-centre study of efficacy and safety of Intratect®, a novel intravenous immunoglobulin preparation.

Clinical and experimental immunology·2010

Same author

Reduced memory B cells in patients with hyper IgE syndrome.

Clinical immunology (Orlando, Fla.)·2008

Same author

Update on the treatment of primary immunodeficiencies.

Allergologia et immunopathologia·2007

Area of Science:

Immunology
Immunotherapy
Disease Mechanisms

Context:

Significant advancements in treating immunological disorders, including Primary Immunodeficiencies (PID) and autoimmune diseases, have emerged.
Improved understanding of disease mechanisms is driving novel therapeutic strategies.
The prognosis and quality of life for patients with these conditions have seen marked improvements.

Purpose:

To review recent therapeutic advancements in immunological diseases.
To highlight the impact of mechanistic insights on treatment development.
To discuss current and future therapeutic interventions for PID and autoimmune diseases.

Summary:

Substitution therapy with intravenous immunoglobulin (IVIg) and hematopoietic stem cell transplantation (HSCT) have transformed PID management.
Immunomodulatory approaches, including anti-proliferative drugs and monoclonal antibodies targeting cytokines or their receptors, show efficacy in autoimmune diseases.
The development pipeline suggests further novel molecules will soon enter clinical practice.

Impact:

Current therapies have substantially improved the prognosis and quality of life for individuals with PID.
Effective immunomodulatory treatments are enhancing patient responses in autoimmune diseases.
The future holds promise for additional therapeutic options, further advancing the treatment landscape for immunological conditions.

Related Experiment Videos