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Mathematica packages for simulation of experimental genetics.

K F Manly1

  • 1Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. kmanly@mcbio.med.buffalo.edu

Bioinformatics (Oxford, England)
|June 27, 2000
PubMed
Summary

New Mathematica software packages enable the simulation and analysis of Mendelian and complex genetic traits in plant and animal experiments. These tools facilitate genetic research by providing advanced computational capabilities for experimental crosses.

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Area of Science:

  • Genetics
  • Bioinformatics
  • Computational Biology

Background:

  • The Mathematica software system is a widely used computational platform.
  • Genetic analysis often requires specialized tools for simulation and data interpretation.

Purpose of the Study:

  • To introduce add-on packages for Mathematica designed for genetic analysis.
  • To provide tools for simulating and analyzing both Mendelian and complex genetic traits.

Main Methods:

  • Development of add-on packages for Mathematica.
  • Implementation of simulation algorithms for genetic crosses.
  • Integration of analysis tools for genetic trait data.

Main Results:

  • The packages allow for the simulation of genetic crosses in plants and animals.

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  • Analysis of both simple Mendelian and complex genetic traits is supported.
  • The software facilitates the study of inheritance patterns and genetic variation.

    • Conclusions:

    • These Mathematica add-on packages offer a valuable resource for genetic research.
    • The tools enhance the capability to analyze genetic traits in experimental settings.
    • Freely available packages promote wider accessibility to advanced genetic analysis methods.