Alkaloids of Andrachne aspera

¹Organic Chemistry Department (CP 160/06), University of Brussels, 50 Avenue F. D. Roosevelt, B-1050 Brussels, Belgium.

|June 28, 2000

Abstract:

Two new 2,6-disubstituted piperidine alkaloids andrachcinine (1) and andrachcinidine (5) have been isolated from Andrachne aspera along with andrachamine and andrachcine (2). The absolute configurations of 1, 2, and 5 were established. (+)-Allosedridine and the new alkaloids (-)-8-epi-8-ethylnorlobelol I (4) and (-)-8-epihalosaline (7) were also identified as constituents of A. aspera. Structures were determined by MS and NMR techniques and by chemical conversions.

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Abstract:

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