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Updated: Aug 7, 2026
The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
Biomarkers of renal cell carcinoma. Past and future considerations
de la Taille A1, Buttyan, Katz
1Department of Urology, Columbia University College of Physicians and Surgeons, Columbia-Presbyterian Medical Center, The Atchley Pavilion, 11th Floor, 161 Fort Washington Avenue, 10032, New York, NY, USA
Abstract:
Renal cancer includes several distinct entities with a range of biologic and clinical behaviors from relatively indolent to extremely aggressive tumors. Although conventional prognostic factors such as stage and grade are quite useful, other clinical, laboratory, and pathologic findings are now believed to have additional predictive values. This article reviews the literature on the potential utility of biomarkers in renal cell carcinoma. To date, only a few biomarkers, such as Ki-67, appeared to be potentially useful for monitoring renal cancer patients. New biomarkers including MN/CA9 and circulating cell detection require further and extensive studies to assess their potential clinical utility.
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