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Pediatric endogenous endophthalmitis
Insights
Pediatric endogenous endophthalmitis, a rare condition, can cause severe vision loss. This study details two cases in infants with Pseudomonas aeruginosa pneumonia, both resulting in total blindness despite aggressive treatment.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Pediatrics
Background:
- Endogenous endophthalmitis is a rare intraocular infection that can lead to severe vision impairment.
- Prompt diagnosis and treatment are crucial for managing this condition, particularly in pediatric patients.
Observation:
- Two cases of pediatric endogenous endophthalmitis are presented: an 8-month-old boy and a 7-day-old girl.
- Both infants had preceding pneumonia caused by Pseudomonas aeruginosa.
- Ocular symptoms included eyelid swelling, purulent discharge, redness, corneal edema, hypopyon, and poor red reflex.
Findings:
- Endophthalmitis developed approximately one week after the onset of pneumonia in both cases.
- Diagnosis occurred 9 days and 3 days after ocular symptom onset, respectively.
- Despite aggressive antimicrobial therapy, both patients experienced total blindness and eyeball atrophy.
Implications:
- This highlights the aggressive nature of Pseudomonas aeruginosa-related endogenous endophthalmitis in infants.
- Emphasizes the need for heightened awareness and rapid intervention in pediatric cases with similar presentations.
- Underscores the potential for devastating visual outcomes even with intensive treatment.
Abstract:
Pediatric endogenous endophthalmitis is a rare disease that can cause serious ophthalmic damage. We describe two cases of pediatric endogenous endophthalmitis. The first occurred in an 8-month-old boy and the second in a 7-day-old girl. These two patients had developed pneumonia due to Pseudomonas aeruginosa infection prior to the onset of ocular symptoms. The interval between the onset of pneumonia and ocular symptoms was 1 week, but endophthalmitis was diagnosed 9 days after the onset of ocular symptoms in the first case and 3 days after the onset of ocular symptoms in the second case. The ocular manifestations included eyelid swelling, purulent discharge, redness, corneal edema, hypopyon, and poor red reflex. Despite treatment with aggressive antimicrobial therapy, both patients became totally blind with eyeball atrophy.