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Related Experiment Videos

Dependence on zolpidem in high dose.

D Vartzopoulos1, V Bozikas, C Phocas

  • 1C Psychiatric Clinic, Aristotle University of Thessaloniki, Greece.

International Clinical Psychopharmacology
|June 28, 2000
PubMed
Summary

Zolpidem may be habit-forming, especially for individuals with a history of substance abuse or personality disorders. High doses of zolpidem led to dependence in four studied cases.

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Area of Science:

  • Pharmacology
  • Psychiatry
  • Addiction Medicine

Background:

  • Zolpidem is a commonly prescribed sedative-hypnotic medication.
  • Concerns exist regarding the potential for zolpidem abuse and dependence.

Observation:

  • This study details four cases of individuals with prior drug or alcohol abuse histories.
  • All patients also had diagnosed personality disorders.

Findings:

  • All four patients developed a dependence on zolpidem.
  • This dependence occurred specifically at high dosages of the medication.

Implications:

  • These cases highlight the risk of zolpidem dependence in vulnerable populations.
  • Clinicians should exercise caution when prescribing zolpidem, particularly to patients with a history of substance abuse or personality disorders.

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