[Cerebrospinal fluid T- and B-lymphocytes in serous meningitis]

By means of PHA-tests and rosette-formation the authors detected in the CSF of patients with serous meningitis T- and B-lymphocytes. They assume that in serous meningitis the penetration of alien antigens into the subarachnoidal space facilitates the migration of T- and B-lymphocytes into the CSF from the lymphoid organs and peripheral blood. On the grounds of these data the authors propose a new concept which assumes that besides the hematoenecephalic barrier, there is also an immunological brain barrier, the morphofunctional basis of which is the CSF with circulating T- and B-lymphocytes and immunoglobulins of different classes.