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Epidemiological background to diabetes.

D R Gamble, K W Taylor

    Acta Endocrinologica. Supplementum
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Juvenile diabetes incidence peaks in autumn and winter, suggesting viral infections in early childhood may trigger the disease after a latent period. Family studies also support an infectious origin for this common childhood condition.

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    Area of Science:

    • Pediatrics
    • Endocrinology
    • Epidemiology

    Background:

    • Seasonal incidence studies indicate juvenile diabetes is primarily acquired during autumn and winter.
    • Recent extensive studies in Great Britain confirm these earlier findings on seasonal patterns.

    Purpose of the Study:

    • To investigate the seasonal incidence of juvenile diabetes.
    • To explore potential initiating and precipitating factors, including viral and infective origins.
    • To understand the age-related incidence patterns and peak occurrences.

    Main Methods:

    • Analysis of seasonal incidence data for juvenile diabetes.
    • Correlation of disease incidence with age in juvenile populations.
    • Examination of familial cases with simultaneous diabetes onset.

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    Main Results:

    • Confirmed seasonal peaks for juvenile diabetes in autumn and winter months.
    • Evidence suggests an early childhood initiating factor, likely viral, followed by a latent period.
    • A peak incidence at age 11 in Britain is observed, potentially linked to precipitating factors.
    • Familial studies lend support to an infective process as a precipitating factor.

    Conclusions:

    • Juvenile diabetes exhibits distinct seasonal incidence, predominantly in colder months.
    • The disease likely results from a combination of early-life viral exposure and later precipitating factors.
    • Infective processes are implicated in the precipitation of juvenile diabetes, particularly in familial cases.