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RadCon: phylogenetic tree comparison and consensus.

J L Thorley1, R D Page

  • 1School of Biological Sciences, University of Bristol, Bristol BS8 1UG, UK. j.l.thorey@bris.ac.uk

Bioinformatics (Oxford, England)
|June 28, 2000
PubMed
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RadCon is a free Macintosh program for phylogenetic tree analysis. It aids in determining cladistic information content, leaf stability, and consensus profiles for supertree construction.

Area of Science:

  • Phylogenetics
  • Computational Biology
  • Bioinformatics

Background:

  • Phylogenetic tree analysis is crucial for understanding evolutionary relationships.
  • Software tools are essential for complex phylogenetic computations.
  • The RadCon program addresses specific needs in phylogenetic analysis.

Purpose of the Study:

  • To introduce RadCon, a Macintosh program for phylogenetic tree manipulation and analysis.
  • To highlight the program's capabilities in assessing tree characteristics and facilitating supertree construction.

Main Methods:

  • The RadCon program utilizes algorithms for phylogenetic tree analysis.
  • It calculates Cladistic Information Content for individual trees.
  • It assesses the stability of leaves across bootstrap trees.

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Main Results:

  • RadCon can determine the Cladistic Information Content of phylogenetic trees.
  • It quantifies the stability of leaves across bootstrap replicates.
  • The program generates strict basic Reduced Cladistic Consensus profiles.
  • It converts tree sets into matrix representations for supertree construction.

Conclusions:

  • RadCon provides a comprehensive suite of tools for phylogenetic tree analysis on Macintosh systems.
  • The program facilitates advanced analyses including consensus profiling and supertree matrix generation.
  • RadCon is freely available, promoting its use in the scientific community.